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Based on broader nanoparticle research, lactoferrin, Angiopep-2, and transferrin receptor-targeting peptides (such as T7) are among the most effective options

Zernecke, A

An updated systematic review with meta-analysis for the clinical evidence of silymarin In this review, 65 papers were analysed and confirmed silymarin to have a number of effects, such as anticancer, antidiabetic, and cardioprotective properties

While more research is needed on liposomal GSH uptake in the CNS, daily liposomal GSH supplementation has been shown to increase GSH levels in whole blood, erythrocytes, plasma and PMBCs within 2 weeks, showing increased passive diffusion of GSH across lipid membranes (Sinha et al., 2018)

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 20% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof